Abstract #1413864: Perioperative Management of Hyperthyroidism in Molar Pregnancy: A Case Report

Hyperthyroidism is a rare complication of molar pregnancy. Perioperative management in hyperthyroidism treatment needs comprehensive approach. A 23-year-old woman with pregnancy at 11 weeks gestation was consulted for perioperative consultation an emergency dilatation and curettage by the obstetrics gynecology department. She had chief complaint intermittent light bleeding from vagina two ago. Due to bleeding, she changed her pads twice day. also complained decreased body weight one month, loss about 4 kg, tremors, irregular menstruation. has general weakness since last month. On physical examination, tachycardic (119 bpm). showed resting tremor on both hands. Significant laboratory findings included hemoglobin concentration 6.7 g/dL, increased transaminase (AST 109 unit/L ALT 81 unit/L), fT4 (7.77 ng/dL), TSH (0.01 micro IU/mL). Propylthiouracil (PTU) 200 mg every hours dexamethasone 5 12 were administered before surgery as while receiving transfusion correct concentration. curetted without any complications. which causes human chorionic gonadotropin. Its alpha subunit similar structure that can bond receptors thyroid cells, leading circulation fT4. Pregnancy termination indicated if patients present significant thyrotoxicosis bleeding. However, carries risk storm surgery. PTU administration aims inhibit peroxidase enzyme converts iodide iodine molecule incorporates into amino acid tyrosine, decreasing T4 production. given steroid (dexamethasone) peripheral conversion T3.